Description

[S(R)]-n-[(S)-[(3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl)Phenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated chiral ligand and organocatalyst, representing a critical tool in modern asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, which are essential for producing single-enantiomer active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and hydroformylation.
• As an organocatalyst for enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions in complex molecule synthesis.
• In the research and development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• For the synthesis of specialty agrochemicals and flavors & fragrances where stereochemistry impacts biological activity or sensory profile.
• In methodological development within academic and industrial laboratories for discovering new catalytic asymmetric processes.
• As a key component in catalyst screening kits for high-throughput experimentation (HTE) in drug discovery.

Basic Information

Product Name	[S(R)]-n-[(S)-[(3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl)Phenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2565792-76-7
Molecular Formula	C41H56NO2PS
Molecular Weight	657.92 g/mol
Synonyms	(S)-N-[(S)-(3-(Benzyloxy)-2-(Dicyclohexylphosphino)phenyl)(phenyl)methyl]-N,2-dimethylpropane-2-sulfinamide; (S)-N-[(S)-(3-(Benzyloxy)-2-(Dicyclohexylphosphino)phenyl)(phenyl)methyl]-2-methylpropane-2-sulfinamide; Chiral Dicyclohexylphosphino-Benzyloxy Sulfinamide Ligand; Asymmetric Phosphine-Sulfinamide Hybrid Ligand; CAS 2565792-76-7
EINECS	Contact for details

Quality Control

Every batch of our [S(R)]-n-[(S)-[(3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl)Phenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide is produced and analyzed under strict quality management protocols to ensure high purity and consistent performance for catalytic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC/NMR), and identity confirmation. Our quality system is designed to support cGMP and ISO standards for advanced chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain catalytic activity and purity. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.