Description

[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl](4-Methoxyphenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in modern asymmetric synthesis. Its primary value lies in enabling highly enantioselective transformations, particularly in the formation of carbon-carbon and carbon-heteroatom bonds, which are critical for producing single-enantiomer pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, specialized ligands to develop novel synthetic routes and optimize catalytic processes.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as cross-couplings and hydrogenations.
• Critical component in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and drug intermediates.
• Use in the development of novel catalytic systems for academic and industrial research in organic chemistry.
• Enabling technology for the production of enantiomerically pure agrochemicals and flavor/fragrance compounds.
• Precursor or auxiliary in the synthesis of complex natural products and specialty chemicals.
• Tool for methodology development in stereoselective synthesis within R&D laboratories.

Basic Information

Product Name	[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl](4-Methoxyphenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2565792-73-4
Molecular Formula	C31H34NO2PS
Molecular Weight	515.64 g/mol
Synonyms	(S)-N-[(R)-(2-(Diphenylphosphino)phenyl)(4-methoxyphenyl)methyl]-N,2-dimethylpropane-2-sulfinamide; (S)-N-((R)-(2-(Diphenylphosphino)phenyl)(4-methoxyphenyl)methyl)-N,2-dimethylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; (S,R)-Sulfinamide Phosphine Ligand; Asymmetric Synthesis Ligand; Sulfinyl Phosphine Ligand; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our [S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl](4-Methoxyphenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive catalytic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity confirmation. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment for material handling.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.