Description

[S(R)]-n-[(S)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl]-(2-Naphthalenyl)Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, crucial for producing single-isomer pharmaceutical intermediates and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to optimize stereocontrolled transformations.

Application

• As a chiral ligand in asymmetric hydrogenation, hydroformylation, and cross-coupling reactions.
• For the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and key intermediates.
• In the development of novel catalytic systems for academic and industrial research.
• As a critical reagent in process chemistry for scaling up chiral compound production.
• For the preparation of high-value agrochemicals requiring specific stereochemistry.
• In the synthesis of specialty chemicals and advanced materials with tailored properties.

Basic Information

Product Name	[S(R)]-n-[(S)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl]-(2-Naphthalenyl)Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-69-8
Molecular Formula	C44H52NO2PS
Molecular Weight	689.92 g/mol
Synonyms	(SR)-N-[(S)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)phenyl](naphthalen-2-yl)methyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(S)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)phenyl](2-naphthyl)methyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; Benzyloxy-Dicyclohexylphosphino-Naphthyl Sulfinamide; Asymmetric Synthesis Ligand CAS 2565792-69-8
EINECS	Contact for details

Quality Control

Every batch of our chiral ligands is produced and tested under strict quality management to ensure consistency and performance in sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identity confirmation. Our quality systems support development under cGMP guidelines where required for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.