Description

[S(R)]-n-[(1S)-1-[2-(Di-tert-Butylphosphanyl)Phenyl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide CAS NO 2565792-66-5 is a sophisticated chiral sulfinamide-phosphine hybrid ligand, representing a high-value building block in modern asymmetric synthesis. Its core value lies in enabling precise stereochemical control in catalytic transformations, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, specialized ligands to develop novel synthetic routes.

Application

This specialized chiral ligand is designed for applications requiring high enantioselectivity and catalytic efficiency.

• Asymmetric Catalysis: As a key ligand in transition metal-catalyzed reactions such as asymmetric hydrogenation, cross-coupling, and hydroformylation.
• Pharmaceutical Intermediate Synthesis: For the production of enantiomerically pure active pharmaceutical ingredients (APIs) and complex chiral molecules.
• Agrochemical Research: In the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Methodology Development: Serving as a benchmark or novel ligand in academic and industrial research for discovering new asymmetric transformations.
• Fine Chemical Production: Enabling the synthesis of high-value chiral flavors, fragrances, and electronic chemicals.
• Catalyst Screening Libraries: As a component in high-throughput screening kits for identifying optimal catalytic conditions.

Basic Information

Item	Details
Product Name	[S(R)]-n-[(1S)-1-[2-(Di-tert-Butylphosphanyl)Phenyl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-66-5
Molecular Formula	C23H40NOPS
Molecular Weight	409.60 g/mol
Synonyms	(S)-N-[(1S)-1-[2-(Di-tert-butylphosphanyl)phenyl]-2,2-dimethylpropyl]-2-methylpropane-2-sulfinamide; Sulfinamide-Phosphine Hybrid Ligand; Chiral tert-Butylsulfinamide Phosphine Ligand; (S)-N-((S)-1-(2-(Di-tert-butylphosphanyl)phenyl)-2,2-dimethylpropyl)-2-methylpropane-2-sulfinamide; Asymmetric Synthesis Ligand; P,S-Bidentate Ligand; CAS 2565792-66-5
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to stringent quality protocols to ensure batch-to-batch consistency and optimal performance in sensitive catalytic applications. Each lot is characterized using advanced analytical techniques, including Chiral HPLC, 1H/31P/13C NMR, and mass spectrometry, to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.