Description

1,3-Benzoxaphosphole, 3-(1,1-Dimethylethyl)-2,3-Dihydro-4-(2-Methoxyphenyl)-2-(1-Methylethyl)-, (2R,3R)- is a high-purity, stereochemically defined organophosphorus compound. This advanced chiral intermediate is critical for the synthesis of complex molecules, offering precise control over stereochemistry in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in areas requiring complex stereocenters.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Catalyst Ligand Precursor: Serves as a sophisticated precursor for chiral ligands in asymmetric catalysis.
• Material Science Research: Investigated for the incorporation of phosphorus heterocycles into advanced polymers and functional materials.
• Academic & Industrial R&D: Essential for methodological studies in organic synthesis and the exploration of new chemical space.

Basic Information

Product Name	1,3-Benzoxaphosphole, 3-(1,1-Dimethylethyl)-2,3-Dihydro-4-(2-Methoxyphenyl)-2-(1-Methylethyl)-, (2R,3R)-
CAS No.	2565792-63-2
Molecular Formula	C21H27O2P
Molecular Weight	342.41 g/mol
Synonyms	(2R,3R)-3-(tert-Butyl)-2,3-dihydro-4-(2-methoxyphenyl)-2-isopropyl-1,3-benzoxaphosphole; (2R,3R)-3-tert-Butyl-2-isopropyl-4-(2-methoxyphenyl)-2,3-dihydro-1,3-benzoxaphosphole; tert-Butyl(2R,3R)-2-isopropyl-4-(2-methoxyphenyl)-2,3-dihydro-1,3-benzoxaphosphol-3-ium-3-ide; Chiral 1,3-Benzoxaphosphole Derivative; (2R,3R)-Dihydrobenzoxaphosphole Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide high-purity material suitable for research and development, with typical purity verified by HPLC and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, and stereochemical integrity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.