Description

[S(R)]-n-[(S)-(1-Naphthalenyl)[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral ligand and organocatalyst, crucial for inducing stereoselectivity in complex synthetic transformations. Its value lies in the precise control it offers over the three-dimensional structure of target molecules, which is essential for developing pharmaceuticals and advanced materials. This high-purity compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for asymmetric synthesis.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., Rh, Pd, Ir) in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Pharmaceutical Intermediate Synthesis: For the stereocontrolled construction of chiral centers in active pharmaceutical ingredients (APIs), particularly for complex drug candidates.
• Organocatalysis: Acting as a chiral sulfinamide catalyst or auxiliary in nucleophilic addition reactions to carbonyl compounds and imines.
• Agrochemical Research: Development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Synthesis of chiral polymers or ligands for advanced materials with specific optical properties.
• Academic & Industrial R&D: A key reagent for methodological development in organic synthesis and exploring new catalytic systems.

Basic Information

Product Name	[S(R)]-n-[(S)-(1-Naphthalenyl)[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-60-9
Molecular Formula	C46H40NO2PS
Molecular Weight	701.86 g/mol
Synonyms	(SR)-N-[(S)-(1-Naphthalenyl)[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]methyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(S)-(1-Naphthyl)[5-(diphenylphosphino)-9,9-dimethylxanthen-4-yl]methyl]-2-methylpropane-2-sulfinamide; Chiral Xantphos Sulfinamide Ligand; Sulfinamide-Derived Xantphos Ligand; (SR,S)-Xantphos Sulfinamide; CAS 2565792-60-9
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and chiral integrity, supporting critical research and development work. Certificates of Analysis (COA) detailing specific analytical results (including HPLC purity, chiral HPLC, 1H/13C/31P NMR, and mass spectrometry) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.