Description

S(R)]-n-[(R)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, crucial for producing optically pure intermediates. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation, hydroformylation, and cross-coupling reactions.
• For the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced drug intermediates.
• In the development of novel agrochemicals and specialty fine chemicals requiring specific stereochemistry.
• As a critical reagent in academic and industrial research for methodology development in organometallic catalysis.
• For the preparation of catalyst libraries used in high-throughput screening for new synthetic routes.

Basic Information

Product Name	S(R)]-n-[(R)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-59-6
Molecular Formula	C34H30NO3PS
Molecular Weight	563.64 g/mol
Synonyms	(R)-tert-Butanesulfinamide, N-[(1R)-1-[6-(Diphenylphosphino)-1,3-benzodioxol-5-yl]-1-naphthalenylmethyl]-; (R)-N-[(R)-[6-(Diphenylphosphino)-1,3-benzodioxol-5-yl](1-naphthyl)methyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; Asymmetric Synthesis Ligand; P,N-Ligand; CAS 2565792-59-6
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by comprehensive analytical techniques including HPLC, NMR, and chiral analysis. A Certificate of Analysis (COA) detailing identity, purity (typically >97%), and enantiomeric excess (ee) is provided with every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) for long-term storage and to maintain optimal reactivity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.