Description

[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl]-1-Naphthalenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a critical component in asymmetric synthesis. Its value lies in enabling highly enantioselective transition metal-catalyzed reactions, crucial for producing single-isomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a privileged ligand for palladium, rhodium, and iridium complexes in cross-coupling, hydrogenation, and hydroformylation reactions.
• Pharmaceutical Intermediate Synthesis: For the enantioselective construction of chiral centers in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Production: In the synthesis of chiral herbicides, fungicides, and pesticides where biological activity is stereospecific.
• Academic & Industrial R&D: A valuable tool for methodology development in organic and organometallic chemistry research.
• Fine Chemical Manufacturing: For the production of high-value, enantiomerically pure flavors, fragrances, and specialty chemicals.

Basic Information

Product Name	[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl]-1-Naphthalenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2565792-58-5
Molecular Formula	C34H34NOPS
Molecular Weight	535.67 g/mol
Synonyms	(SR)-N-[(R)-[2-(Diphenylphosphino)phenyl]-1-naphthalenylmethyl]-N,2-dimethyl-2-propanesulfinamide; (SR,R)-Sulfinamide-Phosphine Ligand; Chiral Sulfinyl Phosphine Ligand; (R)-[2-(Diphenylphosphino)phenyl]-1-naphthalenemethanol-derived Sulfinamide; Asymmetric Sulfinamide Ligand; Hybrid P,N/S=O Ligand; CAS 2565792-58-5
EINECS	Contact for details

Quality Control

Every batch of our chiral ligand is produced and tested under strict quality management to ensure consistency and performance in sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identity confirmation. Our standard quality commitment aligns with cGMP principles for advanced chemical intermediates, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain stability and shelf life.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.