Description

[S(R)]-n-[(S)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl]-(2-Naphthalenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a critical component in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, such as cross-couplings and hydrogenations, enabling the production of single-enantiomer intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries who require precise stereochemical control for developing new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• As a chiral ligand in asymmetric transition metal catalysis, including palladium-catalyzed cross-coupling reactions.
• For the synthesis of enantiomerically pure pharmaceutical intermediates and active ingredients in drug discovery and development.
• In asymmetric hydrogenation processes to create chiral centers with high optical purity.
• As a key reagent in methodology development for academic and industrial research in organic synthesis.
• For the preparation of complex natural products and specialty chemicals requiring defined stereochemistry.
• In the development of catalytic systems for the sustainable manufacturing of fine chemicals.

Basic Information

Product Name	[S(R)]-n-[(S)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl]-(2-Naphthalenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2565792-55-2
Molecular Formula	C41H48NO2PS
Molecular Weight	649.86 g/mol
Synonyms	(S)-N-[(S)-(3-(Benzyloxy)-2-(dicyclohexylphosphanyl)phenyl)(naphthalen-2-yl)methyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; (S)-tert-Butanesulfinamide Derivative; Dicyclohexylphosphino-Benzyloxy-Naphthyl Methyl Sulfinamide; Asymmetric Synthesis Ligand; P,N-Ligand; CAS 2565792-55-2
EINECS	Contact for details

Quality Control

Every batch of our chiral ligands undergoes rigorous quality testing to ensure identity, purity, and enantiomeric excess meet the stringent requirements of advanced synthetic applications. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.