Description

[S(R)]-n-[(R)-[(3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl)Phenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, representing a high-value specialty chemical for advanced synthetic chemistry. Its core value lies in enabling highly enantioselective transformations, particularly in asymmetric catalysis, where it acts as a privileged ligand for transition metals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in the synthesis of complex, bioactive molecules.

Application

• Asymmetric Catalysis: Serving as a chiral ligand for transition metals (e.g., Pd, Rh, Ir) in cross-coupling, hydrogenation, and hydroformylation reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the stereoselective construction of chiral centers in active pharmaceutical ingredients (APIs) and key intermediates.
• Agrochemical Research: Facilitating the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Methodology Development: Used in academic and industrial R&D for discovering new enantioselective synthetic pathways.
• Fine Chemical Production: Applied in the manufacture of high-value chiral flavors, fragrances, and electronic chemicals.
• Ligand Screening Libraries: A key component in high-throughput screening for identifying optimal catalytic systems.

Basic Information

Item	Details
Product Name	[S(R)]-n-[(R)-[(3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl)Phenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2565792-50-7
Molecular Formula	C37H50NO2PS
Molecular Weight	603.82 g/mol
Synonyms	(SR)-N-[(R)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl](Phenyl)Methyl]-N,2-Dimethylpropane-2-Sulfinamide; Chiral Sulfinamide-Phosphine Ligand; (R)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl](Phenyl)Methyl (SR)-N,2-Dimethylpropane-2-Sulfinamide; Dicyclohexylphosphino-Benzyloxy Sulfinamide Ligand; Hybrid P,N,S-Ligand; Asymmetric Catalyst Ligand 2565792-50-7
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.