Description

[S(R)]-n-[(S)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][(3-Benzyloxy-2-(Dicyclohexylphosphino)Phenyl)Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in critical transition metal-catalyzed reactions, enabling the production of single-enantiomer intermediates essential for advanced pharmaceuticals. This compound is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel, optically active molecules.

Application

• As a chiral ligand in asymmetric hydrogenation, hydroformylation, and cross-coupling reactions.
• For the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced intermediates.
• In the development of novel catalytic systems for academic and industrial research.
• For the preparation of chiral agrochemicals and specialty fine chemicals.
• As a critical reagent in methodology development for stereoselective C-C and C-X bond formation.
• In process chemistry for scale-up optimization of enantioselective catalytic steps.

Basic Information

Product Name	[S(R)]-n-[(S)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][(3-Benzyloxy-2-(Dicyclohexylphosphino)Phenyl)Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-48-3
Molecular Formula	C48H70NO3PS
Molecular Weight	772.09 g/mol
Synonyms	(SR)-N-[(S)-[3,5-Bis(1,1-dimethylethyl)-4-methoxyphenyl][[3-(phenylmethoxy)-2-(dicyclohexylphosphino)phenyl]methyl]-2-methyl-2-propanesulfinamide; Chiral Sulfinamide-Phosphine Ligand; (S,R)-DTBM-SEGPHOS-type Sulfinamide; Asymmetric Sulfinamide Ligand; Hybrid P,N,S-Ligand; tert-Butylsulfinamide-Phosphine Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our high-value chiral ligands are produced under strict quality control protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.