Description

[S(R)]-n-[(R)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide ligand, distinguished by its xanthene-based phosphine architecture. This compound is engineered to provide exceptional stereoselectivity and catalytic activity in asymmetric synthesis, a critical requirement for producing high-value enantiopure intermediates. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Catalysis: As a privileged ligand for transition metals (e.g., Rh, Ir, Pd) in enantioselective hydrogenation, C-C bond formation, and other key transformations.
• Pharmaceutical Intermediate Synthesis: For the production of chiral drug candidates and complex bioactive molecules requiring high enantiomeric excess (ee).
• Methodology Development: In academic and industrial research for developing new catalytic protocols and exploring novel reaction pathways.
• Agrochemical Synthesis: In the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Potential use in the synthesis of chiral polymers or as a component in advanced catalytic systems for specialty chemicals.

Basic Information

Product Name	[S(R)]-n-[(R)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-43-8
Molecular Formula	C55H64NO2PS
Molecular Weight	858.13 g/mol
Synonyms	(SR)-N-[(R)-[3,5-Bis(1,1-dimethylethyl)-4-methoxyphenyl][5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]methyl]-2-methyl-2-propanesulfinamide; Xantphos-Derived Chiral Sulfinamide Ligand; (R)-DTBM-SEGPHOS-Type Sulfinamide; Chiral Xanthene Phosphine-Sulfinamide Hybrid Ligand; CAS 2565792-43-8; tert-Butanesulfinamide Xantphos Derivative; (SR,R)-Ligand for Asymmetric Hydrogenation
EINECS	Contact for details

Quality Control

Our production of this high-purity ligand adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and chiral analysis to ensure structural integrity and enantiomeric purity. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided to guarantee reproducible performance in your catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light may degrade performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.