Description

[S(R)]-n-[(R)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]-1-Naphthalenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing single-enantiomer pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation, hydroformylation, and cross-coupling reactions.
• For the development of enantioselective catalysts used in pharmaceutical intermediate synthesis.
• In academic and industrial R&D for exploring novel asymmetric transformations.
• As a key precursor in the synthesis of complex natural products and bioactive molecules.
• For the preparation of high-value specialty chemicals requiring specific chirality.
• In process chemistry for the scale-up and optimization of catalytic routes to chiral APIs.

Basic Information

Product Name	[S(R)]-n-[(R)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]-1-Naphthalenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2565792-42-7
Molecular Formula	C35H34NO3PS
Molecular Weight	579.70 g/mol
Synonyms	(SR)-N-[(R)-[6-(Diphenylphosphanyl)-1,3-benzodioxol-5-yl](naphthalen-1-yl)methyl]-N,2-dimethylpropane-2-sulfinamide; (SR)-N-[(R)-[6-(Diphenylphosphino)-1,3-benzodioxol-5-yl](1-naphthyl)methyl]-N,2-dimethyl-2-propanesulfinamide; Chiral Sulfinamide-Phosphine Ligand; Asymmetric Sulfinamide Ligand; P,N-Ligand; CAS 2565792-42-7
EINECS	Contact for details

Quality Control

Our [S(R)]-n-[(R)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]-1-Naphthalenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, critical for reproducible catalytic performance. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is easily oxidized; prolonged exposure to air should be avoided. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.