Description

[S(R)]-n-[(R)-[(3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl)Phenylmethyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral ligand and organocatalyst, representing a high-value building block in asymmetric synthesis. Its core value lies in enabling precise stereochemical control in critical bond-forming reactions, which is essential for producing enantiomerically pure pharmaceutical intermediates and fine chemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel synthetic routes with high enantioselectivity.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and hydroformylation.
• As an organocatalyst or catalyst precursor for the enantioselective synthesis of complex molecules.
• In the research and development of active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• For the synthesis of agrochemicals and flavors & fragrances where specific enantiomers are desired.
• In academic and industrial research focused on methodology development in organic synthesis.
• As a key intermediate in the preparation of more complex, tailor-made phosphine-sulfinamide ligand libraries.

Basic Information

Product Name	[S(R)]-n-[(R)-[(3-(Benzyloxy)-2-(Dicyclohexylphosphino)Phenyl)Phenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-41-6
Molecular Formula	C37H48NO2PS
Molecular Weight	601.81 g/mol
Synonyms	(S,R)-t-Bu-Sulfinamide-Dicyclohexylphosphino Ligand; (R)-[3-(Benzyloxy)-2-(Dicyclohexylphosphino)phenyl][phenyl]methyl (S)-2-Methylpropane-2-sulfinamide; Chiral Phosphino-Sulfinamide Ligand; Dicyclohexyl(2-((R)-((S)-tert-Butylsulfinyl)(phenyl)methyl)-6-(benzyloxy)phenyl)phosphine; Asymmetric Synthesis Ligand CAS 2565792-41-6
EINECS	Contact for details

Quality Control

Our production of this advanced chiral chemical adheres to stringent quality protocols. Every batch is characterized and purified to meet exacting research and process development standards, with purity typically exceeding 97% (by HPLC/NMR). Identity and chiral purity are confirmed via advanced analytical techniques. A comprehensive Certificate of Analysis (COA), detailing assay, chiral purity, and impurity profile, is provided with each shipment to ensure traceability and support your quality systems.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.