Description

[S(R)]-n-[(1R)-1-[2-(Di-tert-Butylphosphanyl)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide CAS NO 2565792-40-5 is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a critical component in asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, particularly in the pharmaceutical and fine chemical industries where precise stereochemical control is paramount. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and other high-value specialty chemicals requiring advanced catalytic processes.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and C-H activation.
• Key intermediate in the synthesis of enantiomerically pure pharmaceutical compounds and complex natural products.
• Utilized in the research and development of novel catalytic systems for academic and industrial laboratories.
• Critical for the production of agrochemicals and flavors & fragrances where specific stereoisomers are required for activity or sensory profile.
• Used in the preparation of organometallic complexes for material science and polymer chemistry applications.

Basic Information

Product Name	[S(R)]-n-[(1R)-1-[2-(Di-tert-Butylphosphanyl)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-40-5
Molecular Formula	C30H40NOPS
Molecular Weight	493.69 g/mol
Synonyms	(SR)-N-[(1R)-1-[2-(Di-tert-butylphosphanyl)phenyl]phenylmethyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(1R)-1-[2-(Di-tert-butylphosphino)phenyl]benzyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(1R)-1-[2-(Di-tert-butylphosphanyl)phenyl]benzyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(1R)-1-[2-(Di-tert-butylphosphanyl)phenyl]phenylmethyl]-2-methyl-2-propanesulfinamide; (SR)-N-[(1R)-1-[2-(Di-tert-butylphosphanyl)phenyl]benzyl]-2-methyl-2-propanesulfinamide; Chiral Sulfinamide-Phosphine Ligand; Sulfinamide-Phosphine Hybrid Ligand; Asymmetric Synthesis Ligand
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment, supporting cGMP and ISO 9001 compliant workflows for our pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.