Description

[S(R)]-n-[(S)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a critical building block in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, enabling the production of single-enantiomer compounds with superior efficiency. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for creating novel active ingredients and advanced intermediates.

Application

• Asymmetric Catalysis: As a privileged ligand for palladium, rhodium, and iridium complexes in cross-coupling, hydrogenation, and allylic substitution reactions.
• Pharmaceutical Intermediate Synthesis: For the enantioselective construction of chiral centers in drug candidates, including APIs for oncology, CNS disorders, and cardiovascular diseases.
• Agrochemical Research: In the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Methodology Development: A key reagent for academic and industrial research focused on discovering new asymmetric transformations.
• Fine Chemical Production: Enabling the commercial-scale manufacture of chiral flavors, fragrances, and specialty materials.
• Ligand Library Screening: Used in high-throughput screening to identify optimal catalyst systems for challenging stereoselective syntheses.

Basic Information

Product Name	[S(R)]-n-[(S)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-39-2
Molecular Formula	C30H30NO3PS
Molecular Weight	515.60 g/mol
Synonyms	(S)-N-((S)-[6-(Diphenylphosphino)benzo[d][1,3]dioxol-5-yl](phenyl)methyl)-2-methylpropane-2-sulfinamide; (S)-N-[(S)-(6-Diphenylphosphanyl-1,3-benzodioxol-5-yl)-phenyl-methyl]-2-methyl-propane-2-sulfinamide; Sulfinamide-Phosphine Hybrid Ligand; Chiral Sulfinamide Phosphine Ligand; (S,S)-Sulfinamide-DPPBZ Ligand; DPPBZ-Sulfinamide Ligand; Asymmetric Sulfinamide Ligand; CAS 2565792-39-2
EINECS	Contact for details

Quality Control

Every batch of our chiral ligand is produced under strict quality control to ensure consistency and performance in sensitive catalytic applications. We employ advanced analytical techniques including HPLC, 1H/31P/13C NMR, and chiral analysis to verify chemical identity, high purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.