Description

[S(R)]-n-[(S)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide ligand, crucial for enabling highly selective asymmetric transformations in organic synthesis. Its value lies in the precise stereochemical control it imparts, which is essential for producing enantiomerically pure intermediates in pharmaceutical and fine chemical manufacturing. This compound is specifically needed by R&D chemists and process development scientists working on the synthesis of complex, high-value molecules such as active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand in transition metal-catalyzed reactions, including asymmetric hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate Synthesis: Critical for the enantioselective construction of chiral centers in the development of novel APIs and drug candidates.
• Fine Chemical Production: Used in the synthesis of enantiomerically pure flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A valuable tool for methodology development in synthetic organic chemistry laboratories.
• Agrochemical Development: Employed in the synthesis of chiral active ingredients for herbicides, fungicides, and insecticides.
• Process Chemistry Optimization: Enables scalable, efficient, and selective routes for the commercial production of complex molecules.

Basic Information

Product Name	[S(R)]-n-[(S)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-28-9
Molecular Formula	C53H60NO2PS
Molecular Weight	806.09 g/mol
Synonyms	(SR)-N-[(S)-[3,5-Bis(1,1-dimethylethyl)-4-methoxyphenyl][5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]methyl]-2-methyl-2-propanesulfinamide; (SR)-N-[(S)-[3,5-Di-tert-butyl-4-methoxyphenyl][5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]methyl]-2-methylpropane-2-sulfinamide; Chiral Xantphos Sulfinamide Ligand; tert-Butanesulfinamide Xantphos Derivative; Asymmetric Sulfinamide Ligand; (SR,S)-DTBM-Xantphos Sulfinamide
EINECS	Contact for details

Quality Control

Our [S(R)]-n-[(S)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Methyl]-2-Methyl-2-Propanesulfinamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, 1H/31P/13C NMR, and mass spectrometry, to ensure high chemical and chiral purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.