Description

[S(R)]-n-[(S)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. This compound matters for its ability to induce high enantioselectivity in critical transition-metal catalyzed reactions, enabling the production of single-enantiomer intermediates essential for advanced pharmaceuticals and agrochemicals. It is primarily needed by research institutions and industrial R&D departments focused on developing novel active pharmaceutical ingredients (APIs), fine chemicals, and specialty materials where precise stereochemical control is paramount.

Application

• As a chiral ligand in asymmetric transition-metal catalysis, including rhodium- and iridium-catalyzed hydrogenations.
• For the enantioselective synthesis of pharmaceutical intermediates, particularly in the development of chiral amines and amino acid derivatives.
• In academic and industrial research to explore new catalytic methodologies for C-C and C-X bond formation.
• As a critical reagent in the preparation of high-value fine chemicals and specialty agrochemicals requiring specific stereochemistry.
• For the development of custom catalyst systems tailored for specific, challenging asymmetric transformations.

Basic Information

Product Name	[S(R)]-n-[(S)-[6-(Diphenylphosphino)Benzo[D][1,3]Dioxol-5-Yl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-26-7
Molecular Formula	C34H32NO3PS
Molecular Weight	565.66 g/mol
Synonyms	(S)-tert-Butanesulfinamide, N-[(1S)-1-[6-(Diphenylphosphino)-1,3-benzodioxol-5-yl]-1-naphthalenylmethyl]-; (S)-N-[(S)-[6-(Diphenylphosphino)-1,3-benzodioxol-5-yl](1-naphthyl)methyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; Asymmetric Catalyst Ligand; Hybrid P,N-Ligand; tert-Butylsulfinyl Phosphine Ligand; (S,S)-Sulfinamide Phosphine Ligand CAS 2565792-26-7
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral ligand adheres to stringent quality protocols. Every batch is characterized and tested to ensure consistent stereochemical purity and catalytic performance. Standard quality verification includes chiral HPLC analysis, NMR spectroscopy, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97%), and chiral purity is provided with each shipment to support your critical R&D and process development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C/59-77°F) under an inert atmosphere such as argon or nitrogen to ensure long-term stability. The container should be kept in a desiccator to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.