Description

[S(R)]-n-[(S)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][(3-Benzyloxy-2-(Dicyclohexylphosphino)Phenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated, chiral sulfinamide-phosphine hybrid ligand, representing a high-value specialty chemical for advanced synthetic chemistry. Its core value lies in enabling highly enantioselective transformations, particularly in asymmetric catalysis, where it acts as a powerful chiral auxiliary or ligand to control stereochemistry in the synthesis of complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries who are developing novel active pharmaceutical ingredients (APIs) and other high-purity chiral intermediates.

Application

• Asymmetric Catalysis: Serving as a chiral ligand in transition metal-catalyzed reactions, such as asymmetric hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate Synthesis: A key building block or chiral controller in the multi-step synthesis of enantiomerically pure drug candidates and APIs.
• Methodology Development: Used in academic and industrial R&D to develop new enantioselective synthetic protocols and catalytic systems.
• Fine Chemical Production: Enabling the commercial-scale production of chiral flavors, fragrances, and agrochemical intermediates with high optical purity.
• Chiral Resolution & Analysis: Potential use as a chiral selector or derivatizing agent in analytical chemistry for separating enantiomers.

Basic Information

Product Name	[S(R)]-n-[(S)-[3,5-Di-tert-Butyl-4-Methoxyphenyl][(3-Benzyloxy-2-(Dicyclohexylphosphino)Phenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2565792-24-5
Molecular Formula	C48H72NO3PS
Molecular Weight	774.13 g/mol
Synonyms	(SR)-N-[(S)-[3,5-Bis(1,1-dimethylethyl)-4-methoxyphenyl][[3-(phenylmethoxy)-2-(dicyclohexylphosphino)phenyl]methyl]-N,2-dimethyl-2-propanesulfinamide; Chiral Sulfinamide-Phosphine Ligand; tert-Butylsulfinamide-Phosphine Hybrid Ligand; (SR,S)-DTBM-SEGPHOS-type Sulfinamide; Asymmetric Catalyst Precursor; CAS 2565792-24-5
EINECS	Contact for details

Quality Control

Every batch of this high-purity chiral chemical is produced and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral integrity, ensuring it meets the exacting standards required for pharmaceutical R&D and process chemistry. Our quality protocols are designed to support cGMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.