Description

[S(R)]-n-[(1S)-1-[2-(Di-tert-Butylphosphanyl)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide CAS NO 2565792-23-4 is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in modern asymmetric synthesis. Its value lies in its ability to act as a highly effective chiral auxiliary or ligand, enabling the production of enantiomerically pure compounds critical for advanced pharmaceutical and fine chemical manufacturing. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, reliable chiral intermediates for catalysis and complex molecule construction.

Application

• Asymmetric Catalysis: Serving as a privileged chiral ligand in transition metal-catalyzed reactions such as asymmetric hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate Synthesis: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Chiral Auxiliary: Used to induce stereoselectivity in organic transformations, including nucleophilic additions to imines and aldol reactions.
• Agrochemical Research: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Methodology Development: A valuable tool for academic and industrial researchers developing new asymmetric synthetic methodologies.
• Fine Chemical Production: Enabling the commercial-scale manufacture of specialty flavors, fragrances, and advanced materials with defined stereochemistry.

Basic Information

Item	Detail
Product Name	[S(R)]-n-[(1S)-1-[2-(Di-tert-Butylphosphanyl)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-23-4
Molecular Formula	C30H40NOPS
Molecular Weight	493.69 g/mol
Synonyms	(SR)-N-[(1S)-1-[2-(Di-tert-butylphosphanyl)phenyl]phenylmethyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(S)-[2-(Di-tert-butylphosphino)phenyl](phenyl)methyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; Sulfinamide-Phosphine Hybrid Ligand; tert-Butylsulfinamide-Di-tert-butylphosphine Ligand; (SR,S)-DTBM-SEGPHOS Sulfinamide Derivative; Asymmetric Synthesis Ligand; Contact for further synonyms.
EINECS	Contact for details

Quality Control

Every batch of [S(R)]-n-[(1S)-1-[2-(Di-tert-Butylphosphanyl)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide is produced and tested under strict quality management systems to ensure exceptional purity and stereochemical integrity. Our products undergo rigorous analytical testing, including chiral HPLC, NMR, and elemental analysis, to ensure compliance with exacting research and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and full analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The compound is easily oxidized; therefore, containers should be flushed with inert gas after each opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.