Description

[S(R)]-n-[(R)-[2-(Dicyclohexylphosphino)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its primary value lies in enabling highly enantioselective transition metal-catalyzed reactions, which are critical for producing single-isomer pharmaceutical intermediates and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation and other metal-catalyzed C-C and C-X bond-forming reactions.
• Critical component in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex natural products.
• Used in the development of novel catalytic systems for academic and industrial research in organometallic chemistry.
• Facilitates the production of chiral agrochemicals and flavors & fragrances where specific stereochemistry impacts bioactivity or sensory profile.
• Employed in the synthesis of specialty polymers and advanced materials with tailored properties.

Basic Information

Product Name	[S(R)]-n-[(R)-[2-(Dicyclohexylphosphino)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2565792-22-3
Molecular Formula	C29H42NOPS
Molecular Weight	483.70 g/mol
Synonyms	(SR)-N-[(R)-[2-(Dicyclohexylphosphino)phenyl](phenyl)methyl]-2-methylpropane-2-sulfinamide; (SR,R)-N-[(2-(Dicyclohexylphosphino)phenyl)(phenyl)methyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; Dicyclohexylphosphino-Phenyl-Phenylmethyl Sulfinamide; tert-Butanesulfinamide Derivative; Asymmetric Synthesis Ligand; Hybrid P,N-Ligand; CAS 2565792-22-3
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Identity and purity are confirmed by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. The compound is sensitive to oxidation and moisture; ensure containers are sealed properly after each use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.