Description

[S(R)]-n-((S)-(2-(Di-tert-Butylphosphino)Phenyl)(5,6,7,8-Tetrahydro-5,5,8,8-Tetramethyl-2-Naphthalenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated, chiral sulfinamide-phosphine hybrid ligand designed for advanced asymmetric synthesis. This compound matters because it provides exceptional stereocontrol in transition metal-catalyzed reactions, enabling the production of high-value, enantiomerically pure intermediates. Pharmaceutical R&D and fine chemical manufacturers need it for developing novel active pharmaceutical ingredients (APIs) and complex organic molecules where precise chirality is critical.

Application

• As a chiral ligand in asymmetric hydrogenation, cross-coupling, and hydroformylation reactions.
• Critical for the synthesis of enantiomerically pure pharmaceutical intermediates in API development.
• Used in academic and industrial research for developing novel catalytic methodologies.
• Employed in the fine chemicals sector for the production of specialty agrochemicals and flavors/fragrances.
• Facilitates stereoselective C-C and C-X bond formation in complex molecule construction.
• Applicable in process chemistry for scaling up asymmetric transformations.

Basic Information

Product Name	[S(R)]-n-((S)-(2-(Di-tert-Butylphosphino)Phenyl)(5,6,7,8-Tetrahydro-5,5,8,8-Tetramethyl-2-Naphthalenyl)Methyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2561513-58-2
Molecular Formula	C34H52NOPS
Molecular Weight	553.82 g/mol
Synonyms	(S,R)-DTBM-SEGPHOS Sulfinamide; (S,R)-2-(Di-tert-butylphosphino)-N-((S)-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)(2-methylpropan-2-ylsulfinylamino)methyl)aniline; Chiral Sulfinamide-Phosphine Ligand; Asymmetric Hydrogenation Ligand; DTBM-SEGPHOS-based Sulfinamide; tert-Butanesulfinamide-Phosphine Hybrid Ligand; (S,R)-Teth-TRIP Sulfinamide Analog; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by NMR, HPLC, and chiral analysis to confirm structural integrity, high chemical purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool environment. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.