Description

[S(R)]-n-[(S)-(4-Methoxyphenyl)[2-(Di-tert-Butylphosphino)Phenyl]Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, crucial for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals with superior purity and efficacy. This advanced ligand is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel catalytic processes.

Application

• As a chiral ligand in asymmetric hydrogenation and other transition metal-catalyzed reactions.
• Critical for the synthesis of enantiomerically pure pharmaceutical intermediates, including potential drug candidates.
• Used in the development of novel agrochemicals requiring specific stereochemistry for optimal activity.
• Employed in academic and industrial R&D for exploring new asymmetric catalytic methodologies.
• Facilitates the production of chiral fine chemicals and flavors & fragrances.
• Serves as a key scaffold for modifying and tuning catalyst selectivity and activity.

Basic Information

Product Name	[S(R)]-n-[(S)-(4-Methoxyphenyl)[2-(Di-tert-Butylphosphino)Phenyl]Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2561513-53-7
Molecular Formula	C32H42NO2PS
Molecular Weight	535.72 g/mol
Synonyms	(SR)-N-[(S)-(4-Methoxyphenyl)(2-(Di-tert-butylphosphino)phenyl)methyl]-2-methylpropane-2-sulfinamide; (SR)-N-[(S)-(4-Methoxyphenyl)(2-(Di-tert-butylphosphanyl)phenyl)methyl]-2-methylpropane-2-sulfinamide; Sulfinamide-Phosphine Hybrid Ligand; Chiral Sulfinamide Ligand; t-Bu-Sulfinamide Phosphine Ligand; CAS 2561513-53-7
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (ee), and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.