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Benzene, 2,4-Difluoro-1-[1-(4-Methylphenyl)Ethyl]- CAS NO 2484888-98-2


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CAS No.:2484888-98-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Benzene, 2,4-Difluoro-1-[1-(4-Methylphenyl)Ethyl]- is a specialized fluorinated aromatic compound, serving as a high-value intermediate in advanced organic synthesis. Its molecular architecture, featuring a difluorobenzene core and a chiral 1-(4-methylphenyl)ethyl substituent, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical sectors, where precise fluorination is required to modulate bioactivity, metabolic stability, and physicochemical characteristics of target molecules.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives where fluorine substitution is beneficial.
  • Agrochemical Synthesis: Used in developing novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms to enhance lipophilicity, membrane permeability, and environmental stability of the active compounds.
  • Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy, thermal stability, and optical performance.
  • Advanced Polymer Chemistry: Incorporated as a monomer or modifier in the production of specialty polymers, such as polyarylates or polyimides, to impart enhanced chemical resistance, thermal properties, and low dielectric constants.
  • Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in organofluorine chemistry and asymmetric synthesis within academic and industrial laboratories.

Basic Information

Product Name Benzene, 2,4-Difluoro-1-[1-(4-Methylphenyl)Ethyl]-
CAS No. 2484888-98-2
Molecular Formula C15H14F2
Molecular Weight 232.27 g/mol
Synonyms 1-(2,4-Difluorophenyl)-1-(4-methylphenyl)ethane; α-Methyl-4-methylbenzyl-2,4-difluorobenzene; 2,4-Difluoro-1-(1-(p-tolyl)ethyl)benzene; 1-(4-Methylphenyl)ethyl-2,4-difluorobenzene; (1-(2,4-Difluorophenyl)ethyl)-4-methylbenzene; p-Tolyl(2,4-difluorophenyl)ethylethane
EINECS Contact for details

Quality Control

Our Benzene, 2,4-Difluoro-1-[1-(4-Methylphenyl)Ethyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC/GC) ≥ 97.0%
Chiral Purity (Chiral HPLC) Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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