Description

Benzonitrile, 4-(Chloro-1H-1,2,4-Triazol-1-Ylmethyl)- is a high-purity, functionalized benzonitrile derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a unique molecular scaffold for structure-activity relationship (SAR) studies. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to the bioactive triazole moiety.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Advanced Material Development: A building block for functional polymers or organic electronic materials requiring specific nitrile and heterocyclic functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	Benzonitrile, 4-(Chloro-1H-1,2,4-Triazol-1-Ylmethyl)-
CAS No.	2451658-74-3
Molecular Formula	C10H7ClN4
Molecular Weight	218.64 g/mol
Synonyms	4-[(4-Chloro-1H-1,2,4-triazol-1-yl)methyl]benzonitrile; 1-[(4-Cyanophenyl)methyl]-4-chloro-1H-1,2,4-triazole; 4-(4-Chloro-1,2,4-triazol-1-ylmethyl)benzonitrile; 4-((4-Chloro-1H-1,2,4-triazol-1-yl)methyl)benzonitrile; 4-(Chloro-1H-1,2,4-triazol-1-ylmethyl)benzonitrile; p-((4-Chloro-1H-1,2,4-triazol-1-yl)methyl)benzonitrile
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 4-(Chloro-1H-1,2,4-Triazol-1-Ylmethyl)- is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes providing a detailed Certificate of Analysis (COA) with each shipment, which documents critical parameters such as assay purity and impurity profiles. Specifications are aligned with ICH guidelines for impurities, ensuring suitability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.