Description

[S(R)]-n-[(S)-[2-(Diphenylphosphino)Phenyl]-1-Naphthalenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in modern asymmetric synthesis. Its primary value lies in enabling highly enantioselective transition metal-catalyzed reactions, crucial for producing single-isomer pharmaceutical intermediates and fine chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation, hydroformylation, and cross-coupling reactions.
• Critical component in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex natural products.
• Used in the development of novel catalytic systems for academic and industrial research.
• Facilitates the production of chiral agrochemicals and specialty chemicals with high optical purity.
• Employed in methodology development for creating new C-C and C-X bonds with stereocontrol.
• Valuable for process chemistry optimization in scaling up asymmetric transformations.

Basic Information

Product Name	[S(R)]-n-[(S)-[2-(Diphenylphosphino)Phenyl]-1-Naphthalenylmethyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2416748-57-5
Molecular Formula	C34H34NOPS
Molecular Weight	535.67 g/mol
Synonyms	(SR)-N-[(S)-[2-(Diphenylphosphino)phenyl]-1-naphthalenylmethyl]-N,2-dimethyl-2-propanesulfinamide; (SR)-N-[(S)-[2-(Diphenylphosphino)phenyl](naphthalen-1-yl)methyl]-N,2-dimethylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; P,N-Ligand; Asymmetric Synthesis Ligand; CAS 2416748-57-5
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by comprehensive analytical techniques including NMR, HPLC, and chiral analysis. A Certificate of Analysis (COA) detailing purity, assay, and chiral purity is provided with every shipment, supporting cGMP and ISO quality management system principles for traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.