Description

4,4'-Bi-1,3-Benzoxaphosphole, 3,3'-Bis(1,1-dimethylethyl)-2,2'-diethyl-2,2',3,3'-tetrahydro-, (2R,2'R,3R,3'R)-rel- is a high-purity, stereochemically defined organophosphorus compound. It serves as a crucial chiral intermediate or ligand in advanced synthetic chemistry, enabling the production of enantiomerically pure pharmaceuticals and specialty materials. This product is essential for R&D and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise molecular control for asymmetric synthesis.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor in transition metal-catalyzed reactions (e.g., hydrogenation, cross-coupling).
• Pharmaceutical Intermediate: Key building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Intermediate in the production of chiral herbicides, fungicides, or insecticides.
• Material Science Research: Precursor for novel chiral polymers or organophosphorus materials with specific optical properties.
• Academic & Industrial R&D: Tool compound for developing new synthetic methodologies and exploring structure-activity relationships.

Basic Information

Product Name	4,4'-Bi-1,3-Benzoxaphosphole, 3,3'-Bis(1,1-dimethylethyl)-2,2'-diethyl-2,2',3,3'-tetrahydro-, (2R,2'R,3R,3'R)-rel-
CAS No.	2415751-83-4
Molecular Formula	C30H44O2P2
Molecular Weight	498.62 g/mol
Synonyms	rel-(2R,2'R,3R,3'R)-3,3'-Di-tert-butyl-2,2'-diethyl-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole; 3,3'-Di-tert-butyl-2,2'-diethyl-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole (rel-(2R,2'R,3R,3'R)-); Chiral Bi-Benzoxaphosphole Ligand; BIBOP Derivative; AT-BDP Ligand Analog; Chiral Phosphorus Heterocycle; Organophosphorus Catalyst Intermediate
EINECS	Contact for details

Quality Control

Our high-purity chiral chemicals are manufactured under strict quality management systems. Each batch is characterized using advanced analytical techniques including Chiral HPLC, NMR (1H, 13C, 31P), and Mass Spectrometry to confirm identity, enantiomeric excess (ee), and purity. Certificates of Analysis (COA) with full analytical data are provided to ensure compliance with your research and cGMP-grade manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. The material is easily oxidized and light-sensitive. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.