Description

2-((1R)-1-Aminoethyl)Benzenecarbonitrile Hcl is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound matters because its stereochemically defined structure is crucial for developing active pharmaceutical ingredients (APIs) with high enantiomeric purity, directly impacting drug efficacy and safety. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel APIs, particularly in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides for enhanced biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems requiring specific chiral induction.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Fine Chemical Production: Intermediate for manufacturing other specialty chemicals requiring the (R)-1-phenylethylamine moiety.

Basic Information

Item	Detail
Product Name	2-((1R)-1-Aminoethyl)Benzenecarbonitrile Hcl
CAS No.	2411591-49-4
Molecular Formula	C9H10N2•HCl
Molecular Weight	182.65 g/mol
Synonyms	(R)-2-(1-Aminoethyl)benzonitrile hydrochloride; (1R)-1-(2-Cyanophenyl)ethan-1-amine hydrochloride; (R)-α-Methyl-2-cyanobenzylamine hydrochloride; (R)-1-(2-Cyanophenyl)ethylamine hydrochloride; (R)-2-(1-Aminoethyl)benzonitrile HCl; (R)-1-Phenylethylamine-2-carbonitrile hydrochloride; Benzonitrile, 2-[(1R)-1-aminoethyl]-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-((1R)-1-Aminoethyl)Benzenecarbonitrile Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.