Description

5-Fluoro-2-Hydroxy-3-Iodobenzamide is a high-purity, multi-functional halogenated benzamide derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines fluorine and iodine substituents on a phenolic benzamide core, enabling precise modifications in complex molecule construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and coordination chemistry.
• Material Science: Building block for synthesizing functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in the design of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale GMP batches.

Basic Information

Product Name	5-Fluoro-2-Hydroxy-3-Iodobenzamide
CAS No.	2387111-72-8
Molecular Formula	C7H5FINO2
Molecular Weight	280.02 g/mol
Synonyms	3-Iodo-5-fluoro-2-hydroxybenzamide; 5-Fluoro-3-iodosalicylamide; 2-Hydroxy-3-iodo-5-fluorobenzamide; Benzamide, 5-fluoro-2-hydroxy-3-iodo-; AI3-71044; ZINC000103249757; AKOS040759626; BDBM50421352
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Hydroxy-3-Iodobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.