Description

Cyclohexanol, 4-(Difluoromethyl)-, cis- is a high-purity, specialty fluorinated cyclohexanol derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and the synthesis of complex, value-added molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl group enhances lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Acts as a monomer or modifier for creating fluorinated polymers with unique surface properties, chemical resistance, and stability.
• Asymmetric Catalysis & Ligand Development: Utilized as a precursor for developing novel chiral ligands and catalysts used in enantioselective synthesis.
• Chemical Research & Development: A valuable tool compound for exploring new fluorination methodologies and structure-activity relationships (SAR) in academic and industrial labs.

Basic Information

Product Name	Cyclohexanol, 4-(Difluoromethyl)-, cis-
CAS No.	2386979-97-9
Molecular Formula	C7H12F2O
Molecular Weight	150.17 g/mol
Synonyms	cis-4-(Difluoromethyl)cyclohexanol; (1r,4r)-4-(Difluoromethyl)cyclohexan-1-ol; 4-(Difluoromethyl)cyclohexanol (cis-); 4-(Difluoromethyl)-1-cyclohexanol; (cis)-4-(Difluoromethyl)cyclohexanol; rel-(1R,4R)-4-(Difluoromethyl)cyclohexan-1-ol
EINECS	Contact for details

Quality Control

Our Cyclohexanol, 4-(Difluoromethyl)-, cis- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.