Description

5-Bromo-2-Fluoro-3-Methoxycarbonylphenylboronic Acid is a high-purity, multi-functional boronic acid derivative designed for advanced synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the introduction of the bromo-fluoro-methoxycarbonylphenyl moiety can enhance biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs or sensors.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules or inhibitors for studying enzyme function and protein-ligand interactions.
• Ligand Development: The boronic acid group can be utilized to create novel ligands for catalysis or in supramolecular chemistry applications.
• Custom Synthesis & Contract Manufacturing: An essential raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	5-Bromo-2-Fluoro-3-Methoxycarbonylphenylboronic Acid
CAS No.	2377612-08-1
Molecular Formula	C9H7BBrFO4
Molecular Weight	287.87 g/mol
Synonyms	(5-Bromo-2-fluoro-3-(methoxycarbonyl)phenyl)boronic acid; 3-Borono-5-bromo-2-fluorobenzoic acid methyl ester; 5-Bromo-2-fluoro-3-(methoxycarbonyl)benzeneboronic acid; Methyl 5-bromo-2-fluoro-3-boronobenzoate; 2377612-08-1; 5-Br-2-F-3-COOMe-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-3-Methoxycarbonylphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.