Description

3-(Dimethylaminomethyl)-4-Fluorophenylboronic Acid Pinacol Ester is a sophisticated boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group with a dimethylaminomethyl substituent, making it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for Suzuki-Miyaura cross-coupling reactions to create novel fluorinated compounds and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorophenyl moiety is critical for activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: An essential reagent for forming carbon-carbon bonds between aromatic rings, a fundamental reaction in medicinal and process chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(Dimethylaminomethyl)-4-Fluorophenylboronic Acid Pinacol Ester
CAS No.	2377612-07-0
Molecular Formula	C₁₅H₂₃BFNO₂
Molecular Weight	279.16 g/mol
Synonyms	4-Fluoro-3-((dimethylamino)methyl)benzeneboronic acid pinacol ester; (4-Fluoro-3-((dimethylamino)methyl)phenyl)boronic acid pinacol ester; 3-(Dimethylaminomethyl)-4-fluorobenzeneboronic acid pinacol ester; Pinacol [3-((dimethylamino)methyl)-4-fluorophenyl]boronate; B-[4-Fluoro-3-((dimethylamino)methyl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane; 3-(N,N-Dimethylaminomethyl)-4-fluorophenylboronic acid pinacol ester; CAS 2377612-07-0
EINECS	Contact for details

Quality Control

Our 3-(Dimethylaminomethyl)-4-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP, ICH Q7, and REACH regulations for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.