Description

5-Bromo-2,3,4-Trifluorophenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its unique halogenated and fluorinated aromatic structure makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions and material science.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially those requiring halogenated, fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the bromo- and trifluoro-substituents confer specific biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating fluorinated organic semiconductors, liquid crystal molecules, and emissive layers in electronic displays.
• Polymer & Resin Modification: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and other material properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodological development in organoboron chemistry and the creation of compound libraries for screening.
• Ligand & Catalyst Design: Utilized in the synthesis of novel bidentate or tridentate ligands for catalysis, leveraging the boronic acid group for further functionalization.

Basic Information

Product Name	5-Bromo-2,3,4-Trifluorophenylboronic Acid
CAS No.	2377611-88-4
Molecular Formula	C6H2BBrF3O2
Molecular Weight	244.79 g/mol
Synonyms	(5-Bromo-2,3,4-trifluorophenyl)boronic acid; 2,3,4-Trifluoro-5-bromophenylboronic acid; 5-Bromo-2,3,4-trifluorobenzeneboronic acid; Boronic acid, B-(5-bromo-2,3,4-trifluorophenyl)-; 2377611-88-4
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3,4-Trifluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.