Description

2,3-Difluoro-5-Formylphenylboronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure combines a formyl group and a boronic acid moiety on a difluorinated aromatic ring, enabling precise cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require sophisticated intermediates for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoro and formyl groups contribute to biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the production of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new catalytic processes and constructing complex organic architectures.
• Ligand Synthesis: Utilized for preparing specialized ligands used in catalysis and sensor technology.

Basic Information

Item	Detail
Product Name	2,3-Difluoro-5-Formylphenylboronic Acid
CAS No.	2377611-83-9
Molecular Formula	C7H5BF2O3
Molecular Weight	185.92 g/mol
Synonyms	(5-Formyl-2,3-difluorophenyl)boronic acid; 2,3-Difluoro-5-formylbenzeneboronic acid; 5-Borono-2,3-difluorobenzaldehyde; 2,3-Difluorobenzaldehyde-5-boronic acid; (2,3-Difluoro-5-formylphenyl)boronic acid
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the consistency and purity of our boronic acid derivatives. Every batch of 2,3-Difluoro-5-Formylphenylboronic Acid is analyzed using advanced techniques such as HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.