Description

2-Fluorophenyl-1,3-Diboronic Acid, Pinacol Ester is a high-purity, bifunctional boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science: Serves as a monomer or cross-linking agent in the production of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the creation of sophisticated ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized for synthesizing tagged molecules and probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Research: A valuable reagent for CROs and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	2-Fluorophenyl-1,3-Diboronic Acid, Pinacol Ester
CAS No.	2377611-42-0
Molecular Formula	C18H28B2F O4
Molecular Weight	340.04 g/mol
Synonyms	1,3-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorobenzene; 2-Fluoro-1,3-phenylenebis(boronic acid pinacol ester); 2-Fluoro-m-phenylenebis(boronic acid pinacol ester); 2-Fluorobenzene-1,3-diboronic acid bis(pinacol) ester; 2-Fluorobenzene-1,3-diyldiboronic acid pinacol ester; (2-Fluoro-1,3-phenylene)bis(boronic acid) bis(1,1,1',1'-tetramethyleneboronate); 2-Fluoro-1,3-benzenediboronic acid pinacol diester
EINECS	Contact for details

Quality Control

Our 2-Fluorophenyl-1,3-Diboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.