Description

(2-Fluoro-3-Formyl-6-Methoxyphenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a fluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in Suzuki-Miyaura cross-coupling reactions and as a precursor for more elaborate heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymeric materials, including sensors and organic electronic components.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functionality enables efficient palladium-catalyzed coupling with aryl halides, a cornerstone reaction for forming carbon-carbon bonds in complex molecule synthesis.
• Ligand and Catalyst Development: The formyl group allows for further functionalization to create novel bidentate ligands for metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Item	Details
Product Name	(2-Fluoro-3-Formyl-6-Methoxyphenyl)Boronic Acid
CAS No.	2377611-41-9
Molecular Formula	C8H8BFO4
Molecular Weight	197.96 g/mol
Synonyms	2-Fluoro-3-formyl-6-methoxybenzeneboronic acid; (2-Fluoro-6-methoxy-3-formylphenyl)boronic acid; 3-Borono-2-fluoro-6-methoxybenzaldehyde; 2-Fluoro-6-methoxy-3-carboxaldehydephenylboronic acid; 2377611-41-9; Boronic acid, B-(2-fluoro-3-formyl-6-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our (2-Fluoro-3-Formyl-6-Methoxyphenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.