Description

2,3-Difluoro-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-fluorinated boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used to introduce the difluoro-(trifluoromethyl)phenyl moiety into novel herbicides, fungicides, and pesticides, enhancing their metabolic stability and lipophilicity.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as fluorinated polymers and small molecules for OLEDs and semiconductors.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands and organoboron catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	2,3-Difluoro-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2377611-31-7
Molecular Formula	C7H4BF5O2
Molecular Weight	225.91 g/mol
Synonyms	[2,3-Difluoro-5-(trifluoromethyl)phenyl]boronic acid; 2,3-Difluoro-5-(trifluoromethyl)benzeneboronic acid; 5-(Trifluoromethyl)-2,3-difluorophenylboronic acid; Boronic acid, B-[2,3-difluoro-5-(trifluoromethyl)phenyl]-; 2377611-31-7
EINECS	Contact for details

Quality Control

Every batch of our 2,3-Difluoro-5-(Trifluoromethyl)Phenylboronic Acid is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding R&D and scale-up processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.