Description

2-Fluoro-3-(Trifluoroacetamido)Phenylboronic Acid is a sophisticated organoboron building block featuring both a boronic acid and a protected amino group, making it a versatile intermediate for modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions, which are fundamental to pharmaceutical and advanced materials research. This high-purity compound is essential for R&D chemists and process development scientists working in pharmaceutical synthesis, agrochemical discovery, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing fluorinated aromatic systems.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery.
• Agrochemical Research: Serves as a precursor in developing novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Employed in the creation of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Can be utilized in the development of molecular probes and inhibitors for studying biological processes.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-3-(Trifluoroacetamido)Phenylboronic Acid
CAS No.	2377610-93-8
Molecular Formula	C9H6BF4NO3
Molecular Weight	263.96 g/mol
Synonyms	[2-Fluoro-3-(trifluoroacetamido)phenyl]boronic acid; 2-Fluoro-3-[(trifluoroacetyl)amino]benzeneboronic acid; 3-Amino-2-fluorophenylboronic acid trifluoroacetamide; Boronic acid, B-[2-fluoro-3-[(trifluoroacetyl)amino]phenyl]-; 2-Fluoro-3-(trifluoroacetylamino)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(Trifluoroacetamido)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.