Description

Methyl 1-(3-Borono-4-Fluorophenyl)Cyclopropylcarboxylate is a high-value, multifunctional chemical intermediate featuring a cyclopropane ring, a boronic acid ester, and a fluorinated aromatic system. This unique structure makes it a critical building block in modern synthetic chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds, a common motif in drug discovery for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorophenyl and cyclopropyl groups for enhanced biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Methyl 1-(3-Borono-4-Fluorophenyl)Cyclopropylcarboxylate
CAS No.	2377608-18-7
Molecular Formula	C11H12BFO4
Molecular Weight	237.83 g/mol
Synonyms	Methyl 1-(3-borono-4-fluorophenyl)cyclopropanecarboxylate; 1-(3-Borono-4-fluorophenyl)cyclopropanecarboxylic acid methyl ester; (3-(Methoxycarbonyl)cyclopropyl)-4-fluorobenzeneboronic acid; 4-Fluoro-3-(1-(methoxycarbonyl)cyclopropyl)benzeneboronic acid; 3-(1-Methoxycarbonylcyclopropyl)-4-fluorobenzeneboronic acid; 2377608-18-7; Boronic acid, B-[4-fluoro-3-[1-(methoxycarbonyl)cyclopropyl]phenyl]-
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-(3-Borono-4-Fluorophenyl)Cyclopropylcarboxylate is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and GMP (Good Manufacturing Practice) applications. A detailed Certificate of Analysis (COA) providing results for assay, purity (by HPLC), and specific impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.