Description

4-(Methoxycarbonyl)-2-(Trifluoromethyl)Phenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functional groups, enabling precise cross-coupling reactions to construct complex molecular architectures. This advanced intermediate is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create boronic acid-based probes for sensing and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	4-(Methoxycarbonyl)-2-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2377607-76-4
Molecular Formula	C9H8BF3O4
Molecular Weight	247.97 g/mol
Synonyms	2-(Trifluoromethyl)-4-(methoxycarbonyl)benzeneboronic acid; Methyl 4-borono-3-(trifluoromethyl)benzoate; 4-Carbomethoxy-2-trifluoromethylphenylboronic acid; [4-(Methoxycarbonyl)-2-(trifluoromethyl)phenyl]boronic acid; Benzeneboronic acid, 4-(methoxycarbonyl)-2-(trifluoromethyl)-; Methyl 3-(trifluoromethyl)-4-boronobenzoate
EINECS	Contact for details

Quality Control

Our 4-(Methoxycarbonyl)-2-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.