Description

(3-((tert-Butoxycarbonyl)Amino)-5-Fluorophenyl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amino group and a boronic acid functionality. This compound is critical for the synthesis of complex molecules, particularly in the development of novel therapeutics and agrochemicals. It is primarily sought after by R&D scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for applications in Suzuki-Miyaura cross-coupling reactions and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule drugs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds in medicinal chemistry and material science.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the construction of heterobifunctional molecules designed for targeted protein degradation.
• Agrochemical Research: Employed in the discovery and synthesis of new crop protection agents and herbicides.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and target engagement.
• Material Science: Potential precursor for functionalized polymers or organic electronic materials.

Basic Information

Product Name	(3-((tert-Butoxycarbonyl)Amino)-5-Fluorophenyl)Boronic Acid
CAS No.	2377607-30-0
Molecular Formula	C11H15BFNO4
Molecular Weight	255.06 g/mol
Synonyms	3-((tert-Butoxycarbonyl)amino)-5-fluorobenzeneboronic acid; 5-Fluoro-3-((Boc)amino)phenylboronic acid; (3-(Boc-amino)-5-fluorophenyl)boronic acid; Boc-3-Amino-5-fluorophenylboronic acid; N-Boc-3-Amino-5-fluorophenylboronic acid; 3-(N-Boc-amino)-5-fluorophenylboronic acid; (3-Amino-5-fluorophenyl)boronic acid, N-Boc protected; tert-Butyl (5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (Pinacol ester form)
EINECS	Contact for details

Quality Control

Our (3-((tert-Butoxycarbonyl)Amino)-5-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.