Description

4-Fluoro-5-Formyl-2-Methylphenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a fluorinated aromatic ring, makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing and planarizing properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular sensors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	4-Fluoro-5-Formyl-2-Methylphenylboronic Acid
CAS No.	2377606-69-2
Molecular Formula	C9H8BFO3
Molecular Weight	181.97 g/mol
Synonyms	(4-Fluoro-5-formyl-2-methylphenyl)boronic acid; 2-Methyl-4-fluoro-5-formylbenzeneboronic acid; 5-Formyl-4-fluoro-2-methylbenzeneboronic acid; 4-Fluoro-2-methyl-5-formylphenylboronic acid; 4-Fluoro-5-formyl-o-tolylboronic acid; Boronic acid, B-(4-fluoro-5-formyl-2-methylphenyl)-; CAS 2377606-69-2
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Formyl-2-Methylphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.