Description

2-Bromo-6-Fluoro-3-Hydroxyphenylboronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. This compound matters because its unique halogenated and hydroxylated structure enables precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental to constructing complex molecules. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and CNS (Central Nervous System) research.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, OLED (Organic Light-Emitting Diode) materials, and liquid crystals.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Academic & Contract Research: A vital reagent for methodology development and the construction of complex, functionalized aromatic scaffolds in academic and industrial R&D labs.

Basic Information

Product Name	2-Bromo-6-Fluoro-3-Hydroxyphenylboronic Acid Pinacol Ester
CAS No.	2377606-56-7
Molecular Formula	C₁₂H₁₅BBrFO₃
Molecular Weight	316.96 g/mol
Synonyms	2-Bromo-6-fluoro-3-hydroxyphenylboronic acid pinacol ester; (2-Bromo-6-fluoro-3-hydroxyphenyl)boronic acid pinacol ester; 2-Bromo-6-fluoro-3-hydroxybenzeneboronic acid pinacol ester; 5-Bromo-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 2377606-56-7; Boronic acid, B-(2-bromo-6-fluoro-3-hydroxyphenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoro-3-Hydroxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.