Description

5-Bromo-4-Chloro-2-Fluoro-3-Methylphenylboronic Acid CAS NO 2377606-52-3 is a high-value, multi-halogenated phenylboronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures with high efficiency and selectivity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable, high-purity intermediate for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Serves as a precursor for organic electronic materials, including OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the design of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and bioconjugation tools.
• Academic & Contract Research: A vital reagent for method development and discovery chemistry in R&D laboratories.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Fluoro-3-Methylphenylboronic Acid
CAS No.	2377606-52-3
Molecular Formula	C7H6BBrClFO2
Molecular Weight	281.29 g/mol
Synonyms	(5-Bromo-4-chloro-2-fluoro-3-methylphenyl)boronic acid; 2-Fluoro-3-methyl-4-chloro-5-bromophenylboronic acid; 5-Bromo-4-chloro-2-fluoro-3-methylbenzeneboronic acid; Boronic acid, B-(5-bromo-4-chloro-2-fluoro-3-methylphenyl)-; 2377606-52-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-2-Fluoro-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.