Description

3-Acetyl-4-Chlorophenylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling precise cross-coupling reactions to construct complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides and fungicides with targeted activity and improved environmental profiles.
• Material Science Research: Building block for synthesizing organic electronic materials, such as those used in OLEDs and sensors.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the development of activity-based probes and inhibitors for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: A vital raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Acetyl-4-Chlorophenylboronic Acid
CAS No.	2377606-50-1
Molecular Formula	C8H8BClO3
Molecular Weight	198.41 g/mol
Synonyms	(3-Acetyl-4-chlorophenyl)boronic acid; 4-Chloro-3-acetylbenzeneboronic acid; 1-(4-Chloro-3-boronophenyl)ethanone; 3-Acetyl-4-chlorobenzeneboronic acid; Boronic acid, B-(3-acetyl-4-chlorophenyl)-; 3-Acetyl-4-chloro-phenylboronic acid; 4-Chloro-3-acetylphenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Acetyl-4-Chlorophenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, with typical purity levels exceeding 97% (by HPLC). A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.