Description

4-(n-Diethylamino)Methyl-3-Fluorophenylboronic Acid Pinacol Ester is a sophisticated, multi-functional organoboron building block designed for advanced synthetic chemistry. This compound matters because its unique structure, featuring both a boronic ester for cross-coupling and a tertiary amine group, enables the streamlined synthesis of complex molecules, saving significant R&D time. It is primarily needed by pharmaceutical and agrochemical researchers for constructing novel active ingredients, as well as by material scientists developing specialty polymers and electronic chemicals.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the fluorine and amine substituents for enhanced bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Chemical Biology Probe Development: Utilized to synthesize tagged molecules for studying biological pathways and protein-ligand interactions.
• Catalyst Ligand Synthesis: The diethylamino group can be leveraged to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Research: An essential reagent for CROs and fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	4-(n-Diethylamino)Methyl-3-Fluorophenylboronic Acid Pinacol Ester
CAS No.	2377606-38-5
Molecular Formula	C₁₈H₂₉BFNO₂
Molecular Weight	329.24 g/mol
Synonyms	[4-[(Diethylamino)methyl]-3-fluorophenyl]boronic acid pinacol ester; 3-Fluoro-4-[(diethylamino)methyl]benzeneboronic acid pinacol ester; 4-(Diethylaminomethyl)-3-fluorobenzeneboronic acid pinacol ester; B-[4-[(Diethylamino)methyl]-3-fluorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; N,N-Diethyl-1-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanamine; 2377606-38-5; Boronic acid, B-[4-[(diethylamino)methyl]-3-fluorophenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our production of 4-(n-Diethylamino)Methyl-3-Fluorophenylboronic Acid Pinacol Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with REACH and other global regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.