Description

3-[2-(Benzyloxy)Ethoxy]-5-Fluorophenylboronic Acid is a specialized organoboron compound featuring a benzyl-protected ethoxy linker, designed for advanced synthetic applications. This high-value intermediate is critical for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences industry for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic acid coupling partner for the formation of carbon-carbon bonds in complex molecule synthesis.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly those requiring fluorinated aromatic systems.
• Ligand Synthesis: Acts as a precursor for the creation of sophisticated ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological mechanisms.
• Material Science Research: Utilized in the development of organic electronic materials and polymers.
• Custom Synthesis: A building block for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	3-[2-(Benzyloxy)Ethoxy]-5-Fluorophenylboronic Acid
CAS No.	2377606-07-8
Molecular Formula	C15H16BFO4
Molecular Weight	290.10 g/mol
Synonyms	5-Fluoro-3-[2-(benzyloxy)ethoxy]benzeneboronic Acid; [3-[2-(Benzyloxy)ethoxy]-5-fluorophenyl]boronic Acid; 3-(2-Benzyloxyethoxy)-5-fluorophenylboronic Acid; B-[3-[2-(Benzyloxy)ethoxy]-5-fluorophenyl]boronic Acid; 2377606-07-8; AKOS026713023; 3-(2-(Benzyloxy)ethoxy)-5-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-[2-(Benzyloxy)Ethoxy]-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.