Description

(4-(Cyclopropylmethoxy)-2,6-Difluorophenyl)Boronic acid is a specialized organoboron compound featuring a cyclopropylmethoxy and difluoro substitution pattern on the phenyl ring. This unique structure makes it a highly valuable building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is primarily needed by pharmaceutical and agrochemical research & development teams for the efficient construction of complex molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with potentially improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or building block for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Medicinal Chemistry: Employed in the development of molecular probes, enzyme inhibitors, and drug discovery libraries.
• Catalyst Ligand Development: The boronic acid group and substituted aromatic system can be utilized to develop novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis organizations (CSOs) and CDMOs serving the life sciences industry.

Basic Information

Item	Details
Product Name	(4-(Cyclopropylmethoxy)-2,6-Difluorophenyl)Boronic acid
CAS No.	2377605-97-3
Molecular Formula	C10H11BF2O3
Molecular Weight	228.01 g/mol
Synonyms	[4-(Cyclopropylmethoxy)-2,6-difluorophenyl]boronic acid; 2,6-Difluoro-4-(cyclopropylmethoxy)benzeneboronic acid; 4-(Cyclopropylmethoxy)-2,6-difluorobenzeneboronic acid; B-[4-(Cyclopropylmethoxy)-2,6-difluorophenyl]boronic acid; (4-Cyclopropylmethoxy-2,6-difluorophenyl)boronic acid; CAS 2377605-97-3
EINECS	Contact for details

Quality Control

Our (4-(Cyclopropylmethoxy)-2,6-Difluorophenyl)Boronic acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) and handle it in a dry environment to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.