Description

4-Bromo-2-Fluoro-3-Methylphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the halogen and fluorine substituents for enhanced bioactivity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and OFETs, where precise molecular structure is critical.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	4-Bromo-2-Fluoro-3-Methylphenylboronic Acid
CAS No.	2377605-73-5
Molecular Formula	C7H7BBrFO2
Molecular Weight	232.85 g/mol
Synonyms	(4-Bromo-2-fluoro-3-methylphenyl)boronic acid; 2-Fluoro-3-methyl-4-bromophenylboronic acid; 4-Bromo-2-fluoro-m-tolylboronic acid; Boronic acid, B-(4-bromo-2-fluoro-3-methylphenyl)-; 2377605-73-5; 4-Br-2-F-3-MeC6H2B(OH)2
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.