Description

((2S,3S)-4-(Benzyloxy)-3-(tert-Butyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Di-tert-Butylphosphine Oxide is a sophisticated chiral organophosphorus compound, serving as a high-value intermediate and ligand in advanced synthetic chemistry. Its precise stereochemistry and unique phosphine oxide structure make it a critical component for developing novel catalysts and pharmaceuticals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity, stereochemically defined building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Asymmetric Catalysis Ligand: Used as a precursor or ligand in transition metal catalysis for enantioselective synthesis, enabling the production of single-isomer compounds.
• Agrochemical Research: Employed in the development of novel, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Investigated for the synthesis of advanced polymers and functional materials where phosphorus incorporation modifies thermal or electronic properties.
• Process Chemistry Development: Utilized in route scouting and optimization for the commercial-scale manufacturing of complex organic molecules.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	((2S,3S)-4-(Benzyloxy)-3-(tert-Butyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Di-tert-Butylphosphine Oxide
CAS No.	2374143-30-1
Molecular Formula	C28H42O3P2
Molecular Weight	488.58 g/mol
Synonyms	Di-tert-butyl((2S,3S)-4-(benzyloxy)-3-(tert-butyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)phosphine oxide; (2S,3S)-4-(Benzyloxy)-3-tert-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl-di-tert-butylphosphine oxide; Benzodioxaphosphole phosphine oxide derivative; Chiral benzoxaphosphole ligand; (S,S)-Benzyloxy-tert-butyl-dihydrobenzooxaphospholyl-di-tert-butylphosphine oxide
EINECS	Contact for details

Quality Control

Our production of ((2S,3S)-4-(Benzyloxy)-3-(tert-Butyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Di-tert-Butylphosphine Oxide adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.